• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    The implant (1) comprising at least two assembled parts, at least a first part (3) is intended to be movable relative to at least a second part (2). The method comprises the steps of: - designing the implant (1) so that said second component (2) at least partially envelops said first component (3) and at least one connecting bridge (4) connects said first piece to said second piece, each bridge (4) having a section such that it is ruptible; implementing the implant (1) by a process known as "3D printing", consisting in depositing on a plate a layer of powder of material capable of being fused, in effecting a melting of the particles of this layer of powder at locations corresponding to the shape that, at this layer, said first piece (3) and / or said second piece (2) and / or said at least one bridge (4); - to reproduce these operations until the complete constitution of the implant (1), and - to eliminate the non-fused powder particles.
    公开号:FR3049453A1
    申请号:FR1652714
    申请日:2016-03-30
    公开日:2017-10-06
    发明作者:Denys Sournac；Thomas Mosnier；David Ryan
    申请人:Medicrea International SA；
    IPC主号:
    专利说明:

    The present invention relates to a method of manufacturing an implant, in particular vertebral or intervertebral, and the implant obtained by this method.
    It is well known to immobilize two vertebrae relative to one another by means of an intervertebral implant made of rigid material, forming a cage which delimits a housing, this housing being intended to receive one or more bone grafts and / or or cancellous bone chips. Some intervertebral cages are implanted by a posterior approach and are called "PLIF" (Posterior Lumbar Interbody Fusion), others by anterior approach ("ALIF", Anterior Lumbar Interbody Fusion). , and others through a Transforaminal Transforaminal Lumbar Interbody Fusion (TLIF) approach.
    To ensure the anchoring of PLIF or ALIF cages, it is known to provide deployable elements from inside the cage, in the form of claws or anchor points; it is also known to provide a cage having a front portion (that is to say the part of the cage located on the anterior side of the vertebra after implantation) whose height is adapted to be increased after implantation, so as to allow by means of this cage, to restore to lumbar vertebrae their mutual spacing and their anatomical lordosis. Such a cage comprises a basic structure with two branches and a piece forming a wedge, movable between these branches, this wedge piece allowing, by its displacement relative to said branches after implantation of the cage, to carry out the deployment of the anterior part. of the cage.
    Existing cages are made of metal, usually titanium or stainless steel; they have a relatively complex structure, and their manufacture is also complex and expensive.
    A TLIF cage, as described for example in the patent application publication No. EP 2 459 126 in the name of the applicant, must be connected to an instrument for insertion into an intervertebral space, being maintained in the extension of this instrument during its insertion into said intervertebral space, then, once inserted into this space, being able to be pivoted relative to the instrument to take its place in the anterior zone of the intervertebral space, and must finally be separated from the instrument.
    The connection zone of such a cage with the instrument is generally complex and relatively expensive to manufacture. In addition, the existing cages and instruments do not exclude any risk of faulty positioning of the cage.
    It is also well known to place on vertebrae, anchoring members to vertebrae, such as in particular pedicle screws or laminar hooks, for mounting on these vertebrae rigid bars for immobilizing the vertebrae. Such an anchoring member is frequently "polyaxial", that is to say it comprises a distal portion of bone anchorage and a proximal portion of connection to a bar, articulated with respect to this base portion. Said proximal connecting part may be in the form of a bar receiving part (such a proximal part is called "tulip" with reference to its external shape), or may be in the form of an articulated peg, as described in particular by the publication of patent application No. WO 98/55038, also in the name of the applicant.
    Such anchors are also relatively complex and expensive to manufacture.
    The present invention aims to remedy all of the aforementioned drawbacks. For this purpose, the method it relates to manufacturing an implant comprising at least two parts, at least a first part of which is intended to be movable relative to at least a second part, comprises the steps of: designing the implant such that said second piece at least partially envelops said first piece and at least one connecting bridge connects said first piece to said second piece, each bridge having a section such that it is ruptible; implementing the implant by a so-called "3D printing" method, consisting of: depositing a layer of powder of material capable of being fused on a plate, melting the particles of this layer of powder at locations corresponding to the shape that, at this layer, have said first part and / or said second part and / or said at least one bridge, depending on whether this first part, this second part and / or this bridge are present or not. at the level of the section that the implant to be constituted at this layer; to reproduce these operations until the complete constitution of the implant, and to eliminate the non-fused powder particles.
    Said first piece of the implant is thus produced at the same time as said second piece of the implant, with said second piece at least partially enveloping said first piece, as well as at least one bruptible bridge connecting said first piece to said second piece. piece, and the at least partial wrapping of said first piece by said second piece performs an assembly of this first piece to the second piece when each bridge is broken.
    The method according to the invention thus makes it possible to produce an implant relatively simply and quickly, without subsequent assembly operations.
    The ruptibility of each bridge can be obtained by giving each bridge a reduced section, for example less than 1 mm.
    This ability can be achieved in the factory, so that any debris it could generate is eliminated at the manufacturing stage. However, it is conceivable that the rupture of each bridge is done at the time of surgery, by manual action or by means of an instrument. The invention also relates to the implant obtained directly because process. The implant may in particular be an intervertebral cage having an anterior portion whose height is adapted to be increased after implantation; said second part is then constituted by a cage body forming two branches, which is deformable so that the front end portions of these branches are movable relative to each other between a mutual approach position and a mutual spreading position; said first part is then constituted by a spacer wedge engaged between said branches, connected to the cage body by said at least one bridge. The implant may also be a "TLIF" type intervertebral cage; said first part may then be constituted by a part of revolution and said second part be constituted by a cage body forming a bearing for receiving and retaining this part of revolution; the piece of revolution comprises means of connection to an instrument for introduction / positioning of the implant.
    Said piece of revolution and said bearing allow mobility in pivoting of said second piece relative to said first piece, required by this type of intervertebral cage.
    Said piece of revolution may in particular be a cylinder and its connecting means to said instrument may in particular be formed by a through hole forming an internal thread arranged in this piece of revolution. An instrument for placing the cage then comprises a rod having a threaded distal tip intended to be screwed into this through hole of said piece of revolution, the coming of this distal tip threaded against the wall of said second piece defining the bearing allowing to immobilize said second piece in a predetermined position relative to the instrument, in particular in a position in which the second piece is in the longitudinal extension of the instrument. The implant may also be a polyaxial pedicle screw or a polyaxial laminar hook; said first piece is then formed by a connection head or a threaded pin, and said second piece is intended to come into engagement with a vertebra to be treated.
    According to a preferred embodiment of the invention, in this case, one of said first piece and said second piece has a portion of at least partially spherical shape and the other of this first piece and this second piece has a cavity of at least partly spherical shape, intended to receive this portion of at least partially spherical shape, said material bridge being arranged between this portion of at least partially spherical shape and the wall delimiting said cavity of at least partially spherical shape. The invention will be well understood, and other features and advantages thereof will become apparent, with reference to the accompanying drawing, showing, by way of non-limiting examples, several embodiments of the implant it relates.
    FIG. 1 is a perspective view of the implant according to a first embodiment, constituted in this case by an intervertebral cage of ALIF type, of width adapted to lateral placement in an intervertebral space; Figure 2 is an end view, the proximal side; Figure 3 is a schematic view in longitudinal section; Figure 4 is a perspective view of the implant according to a second embodiment, also consisting of an ALIF type intervertebral cage, having a width adapted to a central placement in an intervertebral space; FIG. 5 is a side view of the implant according to a third embodiment, constituted in this case by an intervertebral cage of the TLIF type; Figures 6 to 8 are views of this implant in section along the lines VI-VI of Figure 5 and VII-VII and VIN-VIN of Figure 6; FIGS. 9 to 11 are top views of this implant and the instrument for placing it, during different successive stages of implant placement in an intervertebral space; FIG. 12 is a perspective view of the implant according to a fourth embodiment, constituted in this case by a pedicle screw with articulated proximal pin; FIG. 13 is a view of the implant in longitudinal section passing through the axis of the screw, said proximal pin being immobilized in an axial position; Fig. 14 is a view of the implant similar to Fig. 13, said proximal pin being in an inclined position; and Figs. 15 and 16 are views of the implant according to a fifth embodiment, homologous to Figs. 12 and 13 respectively, in the case of a hinge hook with articulated proximal pin.
    Figures 1 to 3 show an intervertebral cage 1 of the ALIF type, that is to say intended to be implanted by an anterior approach.
    The cage 1 consists of a cage body 2, a wedge 3 and four material bridges 4 connecting this corner 3 and the cage body 2, as shown in Figures 2 and 3. The set of the cage 1 is made by a so-called "3D printing" method, which consists in: depositing on a plate a layer of powder of material capable of being fused, melting the particles of this layer of powder into determined locations, corresponding to a shape that a section of the cage 1 to be made at this layer, - to reproduce these operations until the formation of the complete cage 1, and - to eliminate the non-fused powder particles .
    Said determined locations are therefore delimited, from one layer to another, by the contours that have, at the level of the layer considered, the cage body 2, the wedge 3 and said bridges 4, as far as this cage body 2, this wedge 3 and these bridges 4 are present at the section that the cage 1 to be formed at this layer.
    The wedge 3 is thus produced by this method at the same time as the cage body 2, as well as the bridges 4 of material connecting the wedge 3 to the cage body 2.
    The cage body 2 has a cavity 5 opening on the outside of this body by large openings, this cavity 5 being intended to be filled with one or more cancellous bone grafts or an agglomeration of bone chips spongy.
    This cage body 2 has a parallelepipedal general shape, defining an upper face 6 serrated, a lower face 7 opposite this upper face 6, a proximal end 8 and a distal end 9.
    It will be understood that the terms "upper" and "lower" refer to the position that the cage 1 is intended to have when it is implanted between two vertebrae, the upper face 6 being intended to come into contact with the lower plate of the overlying vertebra while the lower face 7 is intended to come into contact with the upper plate of the underlying vertebra. In the same way, the terms "proxlmal (e)" and "distal (e)" used in the present description are to be considered, in a conventional manner, with respect to the practitioner, "proximal" qualifying a portion of the cage 1 (or other implants described) being closer to this practitioner during the implementation of the implant, and "distal" qualifying a part of the cage being further away from this practitioner during the same implementation .
    It appears that the cage body 2 has the shape of a horizontal U, that is to say it has an upper branch 10, a lower branch 11 vis-à-vis the branch 10 and a portion intermediate 12 connecting these two branches to each other.
    The two branches 10, 11 form anterior ribs 13 and are separated by a longitudinal slot 15 extending from the proximal end 8 towards a distal end 9, this slot 15 interrupting, on the side of this distal end 9, at a curved inner wall that forms said intermediate portion 12. The slot 15 extends in a plane parallel to that in which the branches 10 and 11 extend parallel to each other and opens into the lateral faces of the cage 1, that is to say in the faces thereof which are perpendicular to the upper faces 6 and lower 7. In the embodiment shown, the slot 15 has a thickness, c ' that is to say a dimension perpendicular to said plane, which increases from the proximal end 8 to the distal end 9 of the cage 1.
    With reference to FIG. 3, it appears that the internal faces of the branches 10 and 11, that is to say the vis-à-vis faces of each other, are inclined so as to converge with each other. one towards the other of the proximal end 8 of the cage 1 towards the distal end 9 thereof; these faces form ramps along which the wedge 3 is, after rupture of the bridges 4, able to move, as will be described later, this displacement allowing a spacing of the two branches 10, 11 of one another.
    It also appears in this FIG. 3 that the anterior ribs 13 are transverse to the longitudinal direction of the cage 1 and that they partially close, at the front level of this cage, the space delimited internally by the cage body 2.
    The wedge 3 has a square cross section and forms, on the posterior side of this wedge 3, upper and lower faces coming in close proximity to the inner faces of the branches 10 and 11. These upper and lower faces are able to bear against these faces. during the displacement of the wedge 3, to achieve the anterior separation of the branches 10 and 11. On the anterior side, the wedge 3 has recessed portions having a contour that follows that of the ribs 13. The latter thus form portions of partial wrapping of the wedge 3, ensuring, after rupture of the bridges 4, the retention of this wedge 3 in the space delimited internally by the cage body 2.
    It appears in FIG. 2 that the four bridges 4 are situated near the angles formed by the wedge 3, and it appears in this FIG. 2 and in FIG. 3 that these bridges 4 of the reduced sections, less than 1 mm 2 for each bridge 4, so that these bridges 4 are sized to be ruptible.
    The cage body 2 further has, at its lateral walls, anterior recessed areas 16 which allow its grasping and holding by means of an instrument for placing the cage 1 in an intervertebral space. This instrument (not shown) is in the form of a clamp whose two branches form a gripping jaw of the cage 1 at the recessed areas 16. The instrument also comprises a movable rod longitudinally between the jaws forming said jaw .
    The bridges 4 can be broken at the factory, at the end of manufacture of the cage 1, in which case said rod only carries out the displacement of the wedge 3; these bridges 4 could be broken once the cage 1 is put in place, in which case said rod breaks the bridges 4 and then the displacement of the wedge 3.
    This displacement of the wedge 3 relative to the cage body 2 in the distal direction realizes a spacing of the proximal end portions of the branches 10 and 11, so that the cage 1 is able to give back to the lumbar vertebrae between which it is implanted their mutual spacing and their anatomical lordosis.
    The cage 1 shown in Figures 1 to 3 has a limited width, adapted to an establishment of this cage on a lateral side of an intervertebral space; another cage 1, identical, is in this case placed on the other lateral side of said intervertebral space.
    The cage 21 shown in Figure 4 has a structure similar to that of the cage 1, otherwise it is much wider and adapted to a central placement in an intervertebral space.
    This cage 21 comprises a cage body 22, a wedge 23 and bridges 24 connecting this corner to this cage body, the cage 21 being made by a method identical to that mentioned above used to make the cage 1.
    In this case, the wedge 23 has a U-shape, that is to say has two lateral branches engaged between the lateral portions of the upper and lower branches formed by the cage body 22, and has a central portion connected to the body of cage 22 by bridges 24.
    FIGS. 5 to 8 show an intervertebral cage 31 of the TLIF type, that is to say intended to be implanted by a transforaminal approach, as appears in FIGS. 9 to 11, by means of an instrument 40 .
    The cage 31 comprises a cage body 32 and a cylinder 33 placed inside a bearing that forms a proximal portion 32a of the cage body 32, this proximal portion 32a partially enveloping the cylinder 33 so as to assemble this cylinder to the cage body 32. The cage 31 is made by the same method as that used to manufacture the cages 1 and 21, and the cylinder 33 is connected to the cage body 32 by one or more bridges of material, not visible to the scale of figures.
    The cage body 32 has a generally curved shape, adapted for placement on the anterior side of an intervertebral space 101, as can be seen in FIGS. 9 to 11, and forms a cavity 35 for receiving grafts or wood chips. 'bone.
    It appears in FIGS. 6 and 8 that the cage body 32 forms, at the level of the portion 32a, a curved bore 36 whose curvature is centered on the axis of said bearing, this light extending over approximately 90 °, since a the end slightly set back from the longitudinal axis of the cage body 32 to its other end, located on the concave lateral side of the body 32.
    The cylinder 33 is fitly engaged in said bearing but, after rupture of the bridge or bridges connecting it to the cage body 32, is pivotable in this bearing around an axis perpendicular to the upper and lower faces of the cage body 32 This cylinder 33 is pierced with a hole 37 forming a thread internally, which passes entirely through it, in which is able to be screwed and unscrewed the threaded end of a rod 41 that includes the instrument 40.
    It appears in Figures 9 to 11 that the instrument 40, in addition to this rod 41, comprises a body 42 adapted to bear against said proximal portion 32a. This body 42 is traversed by the rod 41, which is axially movable and rotatable within it.
    The aforementioned bridges are broken at the factory, at the time of manufacture of the cage 31.
    As can be understood with reference to FIGS. 6 to 9, the rod 41 is screwed through the hole 37 until it bears against the cage body 32, with the latter placed in an angular position such that the hole 37 is oriented in parallel to the longitudinal axis of this cage body 32 (this longitudinal axis being that in which the section is cut along the line VII-VII), the cage 31 being thus aligned with the instrument 40. This instrument 40 can therefore be used for the insertion of the cage 31 into an intervertebral space 101 situated between two vertebrae 100, until the cage 31 bears against the anterior ligaments (not shown) connecting these vertebrae 100, as shown in FIG. 9. Once the insertion of the cage 31 made, the rod 41 is unscrewed so as to allow the pivoting of the cage relative to the longitudinal axis of the instrument 40, until the appropriate for the positioning of the cage 31 in the space interv vertebral 101, as shown in FIG.
    The rod 41 can then be unscrewed so as to be extracted from the hole 37, allowing the removal of the instrument 40, as shown in FIG. 11, this unscrewing ensuring an easy separation of the instrument 40 and the cage 31. .
    FIGS. 12 to 14 show a pedicle screw 51 that can be used in particular for fixing a vertebral osteosynthesis material to at least two vertebrae to be immobilized relative to each other, according to a well-known technique, in particular by the publication of a request aforementioned Patent No. WO 98/55038.
    This pedicle screw 51 comprises a body 52, a proximal pin 53 intended to be articulated with respect to this body 52 and a ruptible bridge 54 making a connection of this proximal pin 53 to the body 52. The assembly is produced by the same method 3D printing that used to make the aforementioned cages.
    The body 52 forms a distal thread 55 anchoring to the pedicle of a vertebra and a head 56 defining internally a spherical cavity in which is contained a spherical head 57 of the pin 53. The wall forming the head 56 is closed on this head 57, so that the pin 53 remains assembled to the body 52 when the bridge 54 is broken.
    The pin 53, in addition to this head 57, has a threaded pin body 58, intended to receive a connection piece to a spinal bar and a clamping nut of this connection piece between it and the head 56, according to a technique equally well. known.
    FIGS. 15 and 16 show a laminar hook 61 very similar to the screw 51, thus comprising a body 62, a threaded proximal pin 63 and a releasable bridge 54 for releasable connection of this pin with respect to this body, the assembly being also manufactured by the same method as that mentioned above. The hook body 62 forms a head 66 delimiting a spherical cavity for receiving a corresponding spherical head 67, identical to what has been previously described with respect to the screw 51.
    It appears from the foregoing that the invention provides a method of manufacturing an implant, in particular vertebral or intervertebral, having the decisive advantages of making it possible to achieve an implant relatively simply and quickly, without subsequent assembly operations. The invention has been described above with reference to embodiments given solely by way of example. It goes without saying that it extends to all other embodiments covered by the appended claims.
    权利要求:
    Claims (6)
    [1" id="c-fr-0001]
    1. A method of manufacturing an implant (1, 21, 31, 51, 61), in particular vertebral or intervertebral, this implant (1, 21, 31, 51, 61) comprising at least two assembled parts, of which at least one first piece (3, 23, 33, 53, 63) is intended to be movable relative to at least one second piece (2, 22, 32, 52, 62), characterized in that it comprises the steps of: -conceiving the implant (1, 21, 31, 51, 61) so that said second piece (2, 22, 32, 52, 62) at least partially envelops said first piece (3, 23, 33, 53, 63) and at least one connecting bridge (4, 24, 54, 64) connects said first piece to said second piece, each bridge having a section such that it is ruptible; - Realize the implant (1, 21, 31, 51, 61) by a process called "3D printing", consisting of: - depositing on a tray a layer of powder of material capable of being fused, - to operate a melting the particles of this powder layer at locations corresponding to the shape that, at this layer, said first piece (3, 23, 33, 53, 63) and / or said second piece (2, 22, 32, 52, 62) and / or said at least one bridge (4, 24, 54, 64), depending on whether this first part, this second part and / or this bridge are present or not at the level of the section which the implant to be formed at this layer; - to reproduce these operations until the complete constitution of the implant (1, 21, 31, 51,61), and - to eliminate the non-fused powder particles.
    [2" id="c-fr-0002]
    2. Implant (1) obtained by the method according to claim 1, characterized in that said implant is an intervertebral cage (1, 21) having an anterior portion whose height is adapted to be increased after implantation; said second part is constituted by a cage body (2, 22) forming two branches (10, 11), which is deformable so that the front end portions of these branches (10, 11) are movable one relative to each other between a mutual approach position and a mutual spacing position; said first part is constituted by a spacer (3) engaged between said legs (10, 11), connected to the cage body (2, 22) by said at least one bridge (4).
    [3" id="c-fr-0003]
    3. Implant (31) obtained by the method according to claim 1, characterized in that the implant is an intervertebral cage (31) wherein said first part is constituted by a part of revolution (33) and said second part is constituted by a cage body (32) forming a bearing for receiving and retaining this piece of revolution (33); the piece of revolution (33) comprises means (37) for connecting to an instrument (40) for introducing / positioning the implant (31).
    [4" id="c-fr-0004]
    4. Implant (31) according to claim 3, characterized in that said piece of revolution is a cylinder (33).
    [5" id="c-fr-0005]
    5. Implant (51) obtained by the process according to claim 1, characterized in that this implant is a polyaxial pedicle screw (51) or a polyaxial laminar hook (61); said first piece is formed by a connection head or a threaded pin (53, 63), and said second piece (52, 62) is intended to engage with a vertebra to be treated.
    [6" id="c-fr-0006]
    6. Implant (51, 61) according to claim 5, characterized in that one of said first piece (53, 63) and said second piece (52, 62) has a portion of at least partially spherical shape and the another of this first piece (53, 63) and this second piece (52, 62) has a cavity of at least partially spherical shape intended to receive this portion of at least partially spherical shape, said material bridge (54, 64) being arranged between this portion of at least partially spherical shape and the wall defining this cavity of at least partially spherical shape.
    类似技术:
    公开号 | 公开日 | 专利标题
    EP1299054B1|2007-05-30|Intersomatic implant
    EP1885267B1|2014-04-23|Joint fusion apparatus for the ankle-type joint
    CA2266126C|2005-11-15|Expansive osteosynthesis sheath
    EP3435924B1|2020-05-27|Method for making an implant, notably a vertebral or intervertebral implant, and implant obtained by this method
    FR2697744A1|1994-05-13|Spinal osteosynthesis instrumentation by the anterior route.
    EP0722697A1|1996-07-24|Spinal osteosynthesis device with median hook and vertebral anchoring supports
    FR2831048A1|2003-04-25|Osteosynthesis device for spinal support or correction comprising implant screwed into vertebrae and plate joined to implant without preventing implant screwing rotation
    EP2231074B1|2012-03-07|Intervertebral stabilization assembly for arthrodesis, comprising an impaction cage body, and an ancillary device for implanting same
    FR2831049A1|2003-04-25|Osteosynthesis device comprising implants screwed into two vertebra and plate used to hold and displace the spine
    FR2715293A1|1995-07-28|Vertebral interbody fusion cage.
    FR2833151A1|2003-06-13|BONE ANCHORING IMPLANT WITH POLYAXIAL HEAD
    WO1997023175A1|1997-07-03|Interbody vertebral implant
    FR2729557A1|1996-07-26|INTERSOMATIC CAGE TYPE IMPLANT, AND INSTRUMENTATION AND METHOD FOR ITS INSTALLATION
    FR2913331A1|2008-09-12|Intersomatic cage for being intercalated between two consecutive vertebrae, has elementary cages mounted such that planes of parts form angle when parts are in open position, and faces contact each other when parts are in closed position
    FR2660856A1|1991-10-18|Lower radioulnar prosthesis
    EP2729091A1|2014-05-14|Interbody cage, in particular of the tlif type
    FR2943529A1|2010-10-01|Intervertebral disc prosthesis for patient, has control unit controlling displacement of intermediate body between two positions, and connecting units connecting body with one of two plates and vertebra when body is in one of positions
    FR2866229A1|2005-08-19|Lumbar cage for patient, has branches with front ends spaced angularly by unscrewing of screw and separation of spacing roller from head, where roller supports free front ends of branches against pressure exerted by vertebral body
    FR2790941A1|2000-09-22|INSTRUMENTATION OF RACHIDIAN OSTEOSYNTHESIS WITH PLATE AND PEDICULAR SCREW OR TRANSVERSE CONNECTOR BETWEEN A VERTEBRAL ROD AND A PEDICULAR SCREW
    FR2717066A1|1995-09-15|Bone screw, esp. for spinal support
    FR2835179A1|2003-08-01|Inter-vertebral cage comprises strut, with opposite base faces connected by lateral wall, placed between body vertebrae and strip displaced between position in space and either side space
    CA2657584C|2016-01-05|Intervertebral implant intended for osseous fusion
    FR2903880A1|2008-01-25|Fixation system for use in spinal osteosynthesis, has ring plugged on stem of fixation screw by through bore, and deforming and blocking unit allowing ring to pass from rest form to unstable form and to block cavity in instable form
    FR2965169A1|2012-03-30|Intervertebral cage for treating degenerative rachis, has body interposed between two vertebrae, where cavity is realized in body, and crossing cylindrical opening comprising cross section that is on shape of polygonal
    FR3013211A1|2015-05-22|IMPLANT OF SHOULDER PROSTHESIS, FOR FIXING TOTALLY OR PARTIALLY BY MEANS OF A CEMENT
    同族专利:
    公开号 | 公开日
    US20190105172A1|2019-04-11|
    WO2017168304A1|2017-10-05|
    JP6987776B2|2022-01-05|
    EP3435924A1|2019-02-06|
    AU2017243778B2|2021-04-15|
    AU2017243778A1|2018-10-11|
    ES2809720T3|2021-03-05|
    JP2019509834A|2019-04-11|
    EP3435924B1|2020-05-27|
    FR3049453B1|2018-04-27|
    US10806597B2|2020-10-20|
    引用文献:
    公开号 | 申请日 | 公开日 | 申请人 | 专利标题
    US20030039676A1|1999-02-23|2003-02-27|Boyce Todd M.|Shaped load-bearing osteoimplant and methods of making same|
    WO2005037137A2|2003-10-17|2005-04-28|Therics, Inc.|Spinal cage insert, filler piece and method of manufacturing|
    DE102005004563A1|2005-02-01|2006-08-10|Advanced Medical Technologies Ag|Spreadable implant for preferably dorsal arrangement between the vertebral bodies of the spine|
    DE102005033608A1|2005-07-14|2007-01-25|Medicon Eg, Chirurgiemechaniker-Genossenschaft|Expanding lumbar implant, for insertion between vertebrae, has a body with legs spread apart by a moving slide|
    FR3001381A1|2013-01-31|2014-08-01|Spineart Sa|DEFORMABLE INTERSOMATIC DEVICE|
    DE202015001700U1|2015-03-04|2015-08-04|Marcus Eif|lumbar intervertebral cage leveraging the typical load distribution around the lumbar vertebral end plates|
    IT228979Y1|1992-03-09|1998-06-05|Giannini Sandro|BIODEGRADABLE PROSTHESIS FOR READY FOOT CORRECTION.|
    CA2142636C|1994-02-18|2005-09-20|Salvatore Caldarise|Implantable articles with as-cast macrotextured surface regions and method of manufacturing the same|
    IES77331B2|1997-06-03|1997-12-03|Tecos Holdings Inc|Pluridirectional and modulable vertebral osteosynthesis device of small overall size|
    US6723128B2|2000-10-17|2004-04-20|Chang Jong Uk|Prosthetic device for correcting deformity of spine|
    US6955691B2|2003-11-21|2005-10-18|Kyungwon Medical Co., Ltd.|Expandable interfusion cage|
    US7655046B2|2005-01-20|2010-02-02|Warsaw Orthopedic, Inc.|Expandable spinal fusion cage and associated instrumentation|
    FR2948277B1|2009-07-27|2012-11-16|Medicrea International|ASSEMBLY COMPRISING AN INTERVERTEBRAL IMPLANT FOR IMMOBILIZING A VERTEBRA IN RELATION TO ANOTHER AND A POSITION INSTRUMENT OF THIS IMPLANT|
    MX2014012327A|2012-04-13|2015-05-12|Conformis Inc|Devices and methods for additive manufacturing of implant components.|US10959855B2|2017-05-25|2021-03-30|Stryker European Holdings I, Llc|Fusion cage with integrated fixation and insertion features|
    US11166764B2|2017-07-27|2021-11-09|Carlsmed, Inc.|Systems and methods for assisting and augmenting surgical procedures|
    EP3923829A1|2019-02-14|2021-12-22|SI-Bone, Inc.|Implants for spinal fixation and or fusion|
    法律状态:
    2017-03-10| PLFP| Fee payment|Year of fee payment: 2 |
    2017-10-06| PLSC| Publication of the preliminary search report|Effective date: 20171006 |
    2018-03-30| PLFP| Fee payment|Year of fee payment: 3 |
    2019-03-28| PLFP| Fee payment|Year of fee payment: 4 |
    2020-03-30| PLFP| Fee payment|Year of fee payment: 5 |
    2021-03-30| PLFP| Fee payment|Year of fee payment: 6 |
    优先权:
    申请号 | 申请日 | 专利标题
    FR1652714|2016-03-30|
    FR1652714A|FR3049453B1|2016-03-30|2016-03-30|METHOD FOR MANUFACTURING AN IMPLANT, IN PARTICULAR VERTEBRAL OR INTERVERTEBRAL, AND IMPLANT OBTAINED BY THIS METHOD|FR1652714A| FR3049453B1|2016-03-30|2016-03-30|METHOD FOR MANUFACTURING AN IMPLANT, IN PARTICULAR VERTEBRAL OR INTERVERTEBRAL, AND IMPLANT OBTAINED BY THIS METHOD|
    US16/086,968| US10806597B2|2016-03-30|2017-03-27|Method for making an implant, notably a vertebral or intervertebral implant, and implant obtained by this method|
    AU2017243778A| AU2017243778B2|2016-03-30|2017-03-27|Method for making an implant, notably a vertebral or intervertebral implant, and implant obtained by this method|
    PCT/IB2017/051733| WO2017168304A1|2016-03-30|2017-03-27|Method for making an implant, notably a vertebral or intervertebral implant, and implant obtained by this method|
    JP2018550453A| JP6987776B2|2016-03-30|2017-03-27|Implants, especially how to make vertebrae or facet implants and the implants obtained by such methods|
    EP17713789.0A| EP3435924B1|2016-03-30|2017-03-27|Method for making an implant, notably a vertebral or intervertebral implant, and implant obtained by this method|
    ES17713789T| ES2809720T3|2016-03-30|2017-03-27|Manufacturing procedure of an implant, mainly vertebral or intervertebral, and implant obtained by this procedure|
    [返回顶部]